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U.S: First womb transplant to help infertile women become pregnant


There are women who won’t adopt or have surrogates, for reasons that are personal, cultural or religious.

Most of these women who can not conceive were either born without a womb (uterus) — a condition that affects 1 of every 4,500 newborn girls — or have had their uterus removed or it is damaged, according to reports.

Doctors at the Cleveland Clinic in U.S says, they will attempt to give 10 women the chance to be pregnant by providing them with uterus transplants.

They will  transplant a uterus from a deceased donor into a woman without one.

Screen Capture from the New York Times report
Screen Capture from the New York Times report


The innovative procedure — tentatively scheduled for the next few months — would enable a woman with ovaries but no uterus to become pregnant and deliver a child. Eight women have reportedly started the screening process.

Undergoing a uterus transplant “opens the door to an innovative and promising advancement within reproductive medicine. We believe that tens of thousands of women will benefit from this advancement in the future, while realizing that there are still challenges to overcome before we offer this procedure routinely


See this video (from the CBS network)


Any risks?

Dr. Andreas Tzakis, director of solid organ transplant surgery at a Cleveland Clinic hospital in Weston, Fla., who is spearheading the project, intoned that “These women know exactly what this is about. They’re informed of the risks and benefits. They have a lot of time to think about it, and think about it again. Our job is to make it as safe and successful as possible,”

The transplantation process is not without risks reports say. The women will be given powerful transplant anti-rejection drugs, undergo surgery to implant the uterus and likely face a subsequent surgery to remove the organ after one or two babies are born.

The Process

The process could be complicated and time-consuming. Using in vitro fertilization, the woman’s own eggs would be fertilized with her partner’s sperm and frozen. When she has 10 frozen embryos, she would be put on a waiting list for a transplant, reports say.

Beginning one year after transplant, the embryos would be implanted one at a time until a pregnancy is achieved.

The baby would be born via cesarean section to reduce strain on the transplanted organ. The mother could then decide to have her donor uterus removed or stop taking the anti-rejection drugs, at which point the organ would begin to wither away. Or she could try for a second pregnancy. Because of safety concerns, two is the current limit under consideration.

The hospital plans to perform the procedure 10 times, as an experiment, and then decide whether to continue. this could eventually make the operation readily available in the United States.

In 2014, Sweden became the only country where uterine transplants was completed successfully —  with a uterus from a live donor. Nine women have had them, and four have given birth.

Another is due in January. Their babies were born healthy, though premature. Two transplants failed and had to be removed, one because of a blood clot and the other because of infection.

Two earlier attempts — one in Saudi Arabia, and one in Turkey — failed. Other hospitals, in the United States and in Britain, are also preparing to try the surgery, but are not as close as the team in Cleveland is.

Do you this could be progress for women’s health and family medicine


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This report first appeared here



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